Main structural chromosomal modifications are detectable by karyotyping, however the microarray can’t detect more substantial duplicate range variants of 10 or 20Kb.
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The karyotyping approach depends on mobile lifestyle and metaphase capture if you want to visualize chromosomes. In order to know why only the metaphase, read through this short article: which mobile division section is ideal for karyotyping?
Cell lifestyle, metaphase preparation, mobile harvesting and microscopy are measures by which a chromosome karyotype is ready.
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While, the microarray outcomes are merely a computer generated chromosomal photo exhibiting the hybridization pattern of Management and also the sample DNA on chromosomes.
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A karyotyping is a conventional cytogenetic approach that visualizes the chromosomes while the microarray is a molecular cytogenetic procedure that analyses the chromosomes.
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